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I'm a 43 year old male and I run between 35-45 miles per week, training for new york has gone really well to date and I've missed no sessions (including a 20 miles last sunday). Last night while out I managed to twist my ankle, it's sore today but I'm sure it will recover in time for New York marathon in 18 days. My question is if I miss these last two weeks, will it have much effect on my overall fitness?