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This might sound obvious but perhaps my experience will help somebody: devise a route that stays away from crowded roads. I often run from Paddington Station to my office in London, and I have a choice of a delightful trot through Hyde Park, down Constitution Hill, through St James's Park, across Horseguards Parade and then along the Embankment to the City. The last mile or so past St Pauls and through narrow streets is less enjoyable, but the first five miles are fantastic. Or I can head for Little Venice and pick up the Regent's Canal: apart from one tunnel with no towpath, I get to within a few hundred yards of the office with no motor traffic. Most people's commutes probably offer similar opportunities, but they might take a bit of searching. My big problem is, it's a long run twice a day!