Do antihistamine's effect your ability to run?

I've been suffering with a runny nose for the last two weeks and for the last two days this has transformed in to flu like symptoms. My eyes are burning and I feel like I have a termperature. Am I better off running my first marathon this weekend like this or is it ok to take antihistamines? Do antihistamines negatively impact your ability to run in any way? I haven't taken antihistaines in years so i have between now and the weekend to find one that doesn't make me fall asleep image

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